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sparsentan will lower the extent or impact of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Watch. Sparsentan (a CYP2C19 inducer) decreases exposure of CYP2C19 substrates and cuts down efficacy linked to these substrates.Hou et al (2005) studied the autonomic consequences of modafinil in individuals. They discovered that mod
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